Đánh giá tương quan giữa methyl hóa quá mức gen GSTP1, CDKN2A, RASSF1A và WIF1 với đặc điểm của bệnh nhân ung thư đại trực tràng

Nội dung

* Objectives
- To validate the accuracy of methylation specific polymerase chain reaction (MSP) to assess frequency and distribution of GSTP1, CDKN2A, RASSF1A, and WF1 methylation;
- To analyse their correlation with clinicopathological variables in sporadic adenocarcinomatous colorectal cancer.
* Methods
- Study subject: A total of 248 tumors of sporadic adenocarcinomatous colorectal cancer were collected for analysis.
- Time: 2021
- Site: K Hospital
- Sample size: n = 248